Our research is in organic chemistry and Chemical biology. We design molecular probes to specifically target cancer-relevant facilitative sugar transporters – GLUTs and develop biochemical assays for identifying and understanding links between impaired biological mechanisms and cancer. We heavily rely on organic synthesis and new methodologies to access highly-substituted THF and THP rings as sugar mimics. We use chemical biology to understand molecular interactions that control cellular equilibrium and monitor and adjust impaired biochemical processes.