Our research group focuses on Organic Synthesis and Chemical biology. We develop synthetic methodologies to advance synthetic approaches to highly functionalized heterocycles. Using new and existing synthetic approaches, we design and synthesize sugar-like molecular probes to specifically target cancer-relevant facilitative sugar transporters – GLUTs. We advance our research towards practical applications by developing biochemical assays and advance scientific knowledge by understanding links between impaired biological mechanisms and cancer.

1. Identify experimental conditions that can generate diverse aggregated protein structures from the same proteins.
2. Develop novel tools and techniques to differentiate amongst the varied aggregated species of proteins.
3. Understand the relationship between aggregated protein species and its associated cellular toxicity.