Alexander Apostle, Manoj Perera, Daniel Middleton, Shiyue Fang. Sensitive RNA Synthesis Using Fluoride-Cleavable Groups for Linking and Amino Protection. ChemRxiv [preprint] 2024, open access
Yipeng Yin, Reed Arneson, Yinan Yuan, Shiyue Fang. Long Oligos: Direct Chemical Synthesis of Genes with up to 1,728 Nucleotides. ChemRxiv [preprint] 2024, open access
Shiyue Fang, Reed Arneson, Yipeng Yin, Yinan Yuan. De Novo Synthesis of Error-free Long Oligos. Current Protocols 2024, doi:10.1002/cpz1.70028
Yipeng Yin, Komal Chillar, Alexander Apostle, Bhaskar Halami, Adikari M. D. N. Eriyagama, Marina Tanasova, Shiyue Fang. For Catching-by-Polymerization Oligo Purification: Scalable Synthesis of the Precursors to the Polymerizable Tagging Phosphoramidites. PeerJ Organic Chemistry 2024, 6, e12. open access. ChemRxiv [preprint], open access
Alexander Apostle, Shiyue Fang. Deprotection of m1A Containing RNA Using Triethylamine Hydrogen Fluoride. Nucleosides, Nucleotides, and Nucleic Acids 2024, 1-8
(Invited publication) Shiyue Fang, Komal Chillar, Yipeng Yin, Alexander Apostle, Dhananjani Eriyagama, Shahien Shahsavari, Bhaskar Halami, Yinan Yuan. Oligodeoxynucleotide Synthesis under Non-Nucleophilic Deprotection Conditions. Current Protocols 2024, 4, doi:10.1002/cpz1.983. NSF-PAR
Alexander Apostle, Reed Arneson, Yinan Yuan, Shiyue Fang. The Naturally Occurring m1A RNA Modification Can Be Efficiently Incorporated into RNA by SARS-CoV-2 RdRp. Research Square [preprint] 2023, open access; or Preprints, open access
Yipeng Yin,+ Reed Arneson,+ Alexander Apostle, Adikari Eriyagama, Komal Chillar, Emma Burke, Martina Jahfetson, Yinan Yuan, Shiyue Fang. Long Oligodeoxynucleotides: Chemical Synthesis, Isolation via Catching by Polymerization, Verification via Sequencing, and Gene Expression Demonstration. Beilstein Journal of Organic Chemistry 2023, 19, 1957-1965; open access. ChemRxiv [preprint], open access (+ equal contributors)
Komal Chillar, Yipeng Yin, Alexander Apostle, Shiyue Fang. PEGylated Dmoc Phosphoramidites for Sensitive Oligodeoxynucleotide Synthesis. Organic and Biomolecular Chemistry 2023, 21, 9005-9010. PubMed
Komal Chillar,+ Dhananjani N. A. M. Eriyagama,+ Yipeng Yin,+ Shahien Shahsavari,+ Bhaskar Halami, Alexander Apostle, Shiyue Fang. Oligonucleotide Synthesis under Mild Deprotection Conditions. New Journal of Chemistry 2023, 47, 8714 – 8722. ChemRxiv [preprint], open access (+ equal contributors)
Alexander Apostle, Yipeng Yin, Komal Chillar, Adikari M. D. N. Eriyagama, Reed Arneson, Emma Burke, Shiyue Fang, Yinan Yuan. Effects of Epitranscriptomic RNA Modifications on the Catalytic Activity of SARS-CoV-2 Replication Complex. ChemBioChem 2023, 24, e2023000. ChemRxiv [preprint], open access
Alexander Apostle, Shiyue Fang. Dissolve-Spin: Desalting Oligonucleotides for MALDI MS Analysis. Journal of Mass Spectrometry 2022, 57, e4893. NSF-PAR. PubMed
Komal Chillar, Yipeng Yin, Dhananjani N. A. M. Eriyagama, Shiyue Fang. Determination of Optical Density (OD) of Oligodeoxynucleotides from HPLC Peak Area. PeerJ Analytical Chemistry 2022, 4, e20; open access. ChemRxiv [preprint], open access
Dhananjani N. A. M. Eriyagama, Yipeng Yin, Shiyue Fang. Automated Stepwise PEG Synthesis Using a Base-Labile Protecting Group. Tetrahedron 2022, 119, 132861. NSF-PAR
Logan Mikesell, Dhananjani N. A. M. Eriyagama,+ Yipeng Yin,+ Bao-Yuan Lu, Shiyue Fang. Stepwise PEG Synthesis Featuring Deprotection and Coupling in One Pot. Beilstein Journal of Organic Chemistry 2021, 17, 2976-2982; open access (+ equal contributors)
Shiyue Fang. The Ion Pair Thermal Model of MALDI MS. ChemRxiv [preprint] 2021, October, 19; open access
(Invited publication) Shiyue Fang, Dhananjani Eriyagama, Yinan Yuan, Shahien Shahsavari, Jinsen Chen, Xi Lin, Bhaskar Halami. Dim and Dmoc Protecting Groups for Oligodeoxynucleotide Synthesis. Current Protocols in Nucleic Acid Chemistry 2020, 82, e111. NSF-PAR
Bhaskar Halami, Dhananjani N. A. M. Eriyagama, Komal Chillar, Zack Nelson, Lucas Prehoda, Yipeng Yin, Bao-Yuan Lu, Brett Otto, Liam Haggerty, Shiyue Fang. Linear Oligosulfoxides: Synthesis and Solubility Studies. Tetrahedron Letters 2019, 60, 151306. PubMed
Shahien Shahsavari, Dhananjani Eriyagama, Jinsen Chen, Bhaskar Halami, Yipeng Yin, Komal Chillar, Shiyue Fang. Sensitive Oligodeoxynucleotide Synthesis Using Dim and Dmoc as Protecting Groups. The Journal of Organic Chemistry 2019, 84, 13374-13383. open access PMC6825528
Shahien Shahsavari, Dhananjani N. A. M. Eriyagama, Bhaskar Halami, Vagarshak Begoyan, Marina Tanasova, Jinsen Chen, Shiyue Fang. Electrophilic Oligodeoxynucleotide Synthesis using dM-Dmoc for Amino Protection. Beilstein Journal of Organic Chemistry 2019, 15, 1116-1128; open access
Dhananjani N. A. M. Eriyagama, Shahien Shahsavari, Bhaskar Halami, Bao-Yuan Lu, Fengping Wei, Shiyue Fang. Parallel, Large Scale and Long Synthetic Oligodeoxynucleotide Purification Using the Catching Full-length Sequence by Polymerization Technique. Organic Process Research and Development 2018, 22, 1282-1288. NSF-PAR
Bhaskar Halami, Shahien Shahsavari, Zack Nelson, Lucas Prehoda, Dhananjani N. A. M. Eriyagama, Shiyue Fang. Incorporation of Sensitive Ester and Chloropurine Groups into Oligodeoxynucleotides through Solid Phase Synthesis. ChemistrySelect 2018, 3, 8857-8862. PubMed
Shahien Shahsavari, Chase McNamara, Mark Sylvester, Emily Bromley, Savannah Joslin, Bao-Yuan Lu, Shiyue Fang. Amine Protecting Groups Deprotectable under Nearly Neutral Oxidative Conditions. Beilstein Journal of Organic Chemistry 2018, 14, 1750-1757; open access
Shahien Shahsavari, Travis Wigstrom, James Gooding, Chase McNamara, Shiyue Fang. dM-Dim for Carboxylic Acid Protection. Tetrahedron Letters 2018, 59, 1763-1766. PubMed
Ashok Khanal, Shiyue Fang. Solid Phase Stepwise Synthesis of Polyethylene Glycol. Chemistry—A European Journal 2017, 23, 1533-1542. PubMed
Shahien Shahsavari, James Gooding, Travis Wigstrom, Shiyue Fang. Formation of Hindered Arylcarbamates using Alkyl Aryl Carbonates under Highly Reactive Conditions. ChemistrySelect 2017, 2, 3959-3963. PubMed
Xi Lin,+ Jinsen Chen,+ Shahien Shahsavari,+ Nathanael Green, Deepti Goyal, Shiyue Fang. Synthesis of Oligodeoxynucleotides Containing Electrophilic Groups. Organic Letters 2016, 18, 3870-3873 (+ equal contributors). PubMed
Shahien Shahsavari,+ Jinsen Chen,+ Travis Wigstrom, James Gooding, Alexander Gauronskas, Shiyue Fang. Tritylation of Alcohols under Mild Conditions without Using Silver Salts. Tetrahedron Letters 2016, 57, 3877-3880 (+ equal contributors)
Ashok Khanal,+ Fei Long,+ Bin Cao, Reza Shahbazian-Yassar, Shiyue Fang. Evidence of Splitting 1,2,3-Triazole into an Alkyne and Azide by Low Mechanical Force in the Presence of Other Covalent Bonds. Chemistry—A European Journal 2016, 22, 9760-9767. (+ equal contributors). open access
Durga Pokharel, Shiyue Fang. Polymerizable Phosphoramidites with Acid-Cleavable Linker for Eco-Friendly Synthetic Oligodeoxynucleotide Purification. Green Chemistry 2016, 18, 1125-1136. open access. open access
Fei Long, Bin Cao, Ashok Khanal, Shiyue Fang, Reza Shahbazian-Yassar. Modification of a Single-Molecule AFM Probe with Highly Defined Surface Functionality. Beilstein Journal of Nanotechnology 2014, 5, 2122-2128; open access
Durga Pokharel, Shiyue Fang. A Highly Convenient Procedure for Oligodeoxynucleotide Purification. The Open Organic Chemistry Journal 2014, 8, 15-18; open access
Durga Pokharel, Suntara Fueangfung, Mingcui Zhang, Shiyue Fang. Peptide and Peptide Nucleic Acid Syntheses Using a DNA/RNA Synthesizer. Biopolymers: Peptide Science 2014, 102, 487-493
Mingcui Zhang, Durga Pokharel, Shiyue Fang. Purification of Synthetic Peptides Using a Catching Full-length Sequence by Polymerization Approach. Organic Letters 2014, 16, 1290-1293
Suntara Fueangfung, Yinan Yuan, Shiyue Fang. Denaturing Reversed-Phase HPLC Using a Mobile Phase Containing Urea for Oligodeoxynucleotide Analysis. Nucleosides, Nucleotides and Nucleic Acids 2014, 33, 481-488
Durga Pokharel, Yinan Yuan, Suntara Fueangfung, Shiyue Fang. Synthetic Oligodeoxynucleotide Purification by Capping Failure Sequences with a Methacrylamide Phosphoramidite Followed by Polymerization. RSC Advances 2014, 4, 8746–8757