Students/postdoc authors 

Adhikari R, Yang M, Saikia N, Dutta C, Alharbi WFA, Shan Z, Pandey R, and Tiwari A. Acetylation of Aβ42 at Lysine 16 Disrupts Amyloid Formation.  ACS Chem Neurosci. (2020) 11(8):1178-1191. DOI: 10.1021/acschemneuro.0c00069. PMID: 32207962

Mazi W, Adhikari R, Zhang Y, Xia S, Fang M, Luck RL, Tajiri M, Tiwari A, Tanasova M, and Liu H. Fluorescent Probes with High pKa Values Based on Traditional, Near-infrared Rhodamine, and Hemicyanine Fluorophores for Sensitive Detection of Lysosomal pH Variations. Methods (2019) 168: 40-50. DOI:

Chen T-H, Zhang S, Jaishi M, Adhikari R, Bi J, Fang M, Xia S, Zhang Y, Luck RL, Pati R, Lee H-M, Luo F-T, Tiwari A, and Liu H.  New Near-Infrared Fluorescent Probes with Single-Photon Anti-Stokes-Shift Fluorescence for Sensitive Determination of pH Variances in Lysosomes with a Double-Checked Capability. ACS Appl. Bio Mater. (2018) 1(3): 549-560.

Fang M, Adhikari R, Bi J, Mazi W, Dorh N, Wang J, Conner N, Ainsley J, Karbencheva-Christova TG, Luo F-T, Tiwari A, and Liu H. Fluorescent probes for sensitive and selective detection of pH changes in live cells in visible and near-infrared channels. J Mater. Chem. B (2017) 5(48): 9579-9590.

Zhang J, Li C, Dutta C, Fang M, Zhang S, Tiwari A, Werner T, Luo F-T, Liu H. A novel near-infrared fluorescent probe for sensitive detection of β-galactosidase in living cells. Analytica Chimica Acta (2017) 968: 97-104.

Zhang S, Adhikari R, Fang M, Dorh N, Li C, Jaishi M, Zhang J, Tiwari A, Pati R, Luo F-T, and Liu H.  Near-Infrared Fluorescent Probes with Large Stokes Shifts for Sensing Zn(II) Ions in Living Cells. ACS Sensors (2016) 1(12): 1408-1415.

Zhang J, Yang M, Mazi W, Adhikari K, Fang M, Xie F, Valenzano L, Tiwari A, Fen-Tair L, and Liu H. Unusual fluorescent responses of Morpholine-functionalized fluorescent probes to pH via manipulation of BODIPY’s HOMO and LUMO energy orbitals for intracellular pH detection. ACS Sens. (2016) 1(2): 158-165.

Dorh N, Zhu S, Dhungana KB, Pati R, Fen-Tair L, Liu H, and Tiwari ABODIPY-based fluorescent probes for sensing protein surface-hydrophobicity. Sci Rep. (2015) 5:18337. DOI:10.1038/srep18337

Dutta C, Yang M, Long F, Shahbazian-Yassar R, and Tiwari A.Preformed seeds modulate native insulin aggregation kinetics . J Phys. Chem. B (2015) 119 (49): 15089-15099.

Yang M, Dutta C, and Tiwari ADisulfide-bond scrambling promotes amorphous aggregates in lysozyme and bovine serum albumin. J Phys. Chem. B (2015) 119 (10): 3969-3981.

Zhang J, Yang M, Li C, Dorh N, Xie F, Luo FT, Tiwari A, and Liu H.Near-infrared fluorescent probes based on piperazine-functionalized BODIPY dyes for sensitive detection of lysosomal pH. J Mater. Chem. B (2014) 3 (10): 2173-2184.

ZhaoY, Xing Q, Janjanam J, He K, Long F, Low K.-B, Tiwari A, Zhao F, Shahbazian-Yassar R, Friedrich C, Shokuhfar T. Facile electrochemical synthesis of antimicrobial TiO2 nanotube arrays.International Journal of Nanomedicine. (2014) 9 (1): 5177-5187.

Vegesna G, Janjanam J, Bi J, Luo F-T, Zhang J, Olds C, Tiwari A, and Liu H. pH-activatable near-infrared fluorescent probes for detection of lysosomal pH inside living cells. J Mater. Chem. B (2014) 2: 4500-4508.

Ding X, Janjanam JTiwari A, Thompson M, and Heiden PA. Peptide-directed self-assembly of functionalized polymeric nanoparticles Part I: Design and self-assembly of peptide-copolymer conjugates into nanoparticle fibers and 3D scaffolds. Macromol. Biosci. (2014) 14(6): 853-871.

Low HP, Tiwari A, Janjanam J, Qiu L, Chang C-I, Strohsnitter WC, Norwitz ER, Tam SW, Evans JE, Green KM, Paulo JA, Lambe M, and Hsieh CC. Screening preeclamptic cord plasma for proteins associated with decreased breast cancer susceptibility. Genomics Proteomics Bioinformatics (2013) 11(6): 335-344.

Morfini GA, Bosco DA, Brown H, Gatto R, Kaminska A, Song Y, Molla L, Baker L, Marangoni MN, Berth S, Tavassoli E, Bagnato C,Tiwari A, Hayward LJ, Pigino GF, Watterson DM, Huang C-F, Banker G, Brown Jr. RH, and Brady ST. Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase. PLoS ONE(2013) 8(6): e65235.

Zhu S, Zhang J, Janjanam J, Vegesna G, Luo F-T, Tiwari A, and Liu H. Highly Water-soluble BODIPY-based fluorescent probes for sensitive fluorescent sensing of zinc(II). J Mater.Chem. B (2013) 1 : 1722-1728.

Chen N, Xiang Xu, Tiwari A, and Heiden PA. Tuning Thermoresponsive Behavior of Diblock Copolymers And Their Gold Core Hybrids. Part 1. Importance of Placement of Amphiphilic End Groups on the Diblock Copolymers J Colloid Interface Sci (2013) 391 : 60-69.

Zhu S, Zhang J, Janjanam J, Bi J, Vegesna G, Tiwari A, Luo Fen-Tair, Wei J and Liu H. Highly Water-soluble, near-infrared emissive BODIPY polymeric dye bearing RDG peptide residues for cancer imaging. Analytica Chimica Acta (2013) 758 : 138-144.

Zhu S, Dorh N, Zhang J, Vegesna G, Li H, Luo F-T, Tiwari A, and Liu H. Highly Water-soluble Neutral Near-infrared Emissive BODIPY Polymeric Dyes. Journal of Materials Chemistry (2012) 22: 2781-2790.

Zhu S, Zhang J, Vegesna G, Tiwari A, Luo F-T, Zeller M, Luck R, Li H, Green SA, and Liu H. Controlled Knoevenagel reactions of methyl groups of 1,3,5,7-tetramethyl BODIPY dyes for unique BODIPY dyes.RSC Advances (2012) 2: 404-407.

Molnar KS, Karabacak NM, Johnson JL, Wang Q, Tiwari A, Hayward LJ, Coales SJ, Hamuro Y, and Agar JN. A common property of amyotrophic lateral sclerosis-associated variants: Destabilization of the Cu/Zn superoxide dismutase electrostatic loop. J Biol Chem. (2009) 284(45): 30965-30973.

Tiwari A, Liba A, Sohn SH, Seetharaman SV, Bilsel O, Matthews CR, Hart PJ, Valentine JS, and Hayward LJ. Metal deficiency increases aberrant hydrophobicity of mutant superoxide dismutases that cause amyotrophic lateral sclerosis. J Biol Chem. (2009) 284(40): 27746-27758.

Karabacak NM, Li L, Tiwari A, Hayward LJ, Hong P, Easterling ML, and Agar JN. Sensitive and specific identification of wild-type and variant proteins from 8 to 669 kDa using top-down mass spectrometry.Mol Cell Proteomics. (2009) 8(4): 846-856.

Morfini GA, Burns M, Binder LI, Kanaan NM, Lapointe N, Bosco DA, Brown RH Jr, Brown H, Tiwari A, Hayward L, Edgar J, Nave KA, Garberrn J, Atagi Y, Song Y, Pigino G, and Brady ST. Axonal Transport Defects in Neurodegenerative Diseases. J Neurosci. (2009) 29(41): 12776-12786. [REVIEW]

Cao X, Antonyuk S, Seetharaman SV, Whitson LJ, Taylor AB, Holloway SP, Strange RW, Doucette PA, Valentine JS, Tiwari A, Hayward LJ, Padua S, Cohlberg JA, Hasnain SS, and Hart PJ.Structures of the G85R variant of SOD1 in familial ALS. J Biol Chem.(2008) 283(23): 16169-16177.

Shaw BF, Lelie HL, Durazo A, Nersissian AM, Xu G, Chan PK, Gralla EB, Tiwari A, Hayward LJ, Borchelt DR, Valentine JS, and Whitelegge JP. Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxides dismutase-1. J Biol Chem. (2008) 283(13): 8340-8350.

Watanabe S, Nagano S, Duce J, Kiaei M, Li Q-X, Tucker SM, Tiwari A, Brown RH, Jr., Beal MF, Hayward LJ, Culotta VC, Yoshihara S, Sakoda S, and Bush AI. Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis. Free Radic Biol Med. (2007) 42(10): 1534-1542.

Tiwari A and Bhat R. Stabilization of yeast hexokinase A by polyol osmolytes: Correlation with physicochemical properties of aqueous solutions. Biophys Chem. (2006) 124(2): 90-99.

Tiwari A and Hayward LJ. Mutant SOD1 instability: Implications for toxicity in Amyotrophic Lateral Sclerosis. Neurodegener Dis. (2005) 2(3-4): 115-127. [REVIEW]

Tiwari A, Xu Z, and Hayward LJ. Aberrantly increased hydrophobicity shared by mutants of Cu/Zn superoxide dismutase in familial amyotrophic lateral sclerosis. J Biol Chem. (2005) 280(33): 29771-29779.
(Featured in August 19, 2005 issue of the Journal of Biological Chemistry as “Paper of the Week” (J Biol Chem. (2005) 280: e99939)).

Rodriguez JA, Shaw BF, Durazo A, Sohn SH, Doucette PA, Nerissian AM, Faull KF, Eggers DK, Tiwari A, Hayward LJ, and Valentine JS.Destabilization of apoprotein is insufficient to explain Cu, Zn-superoxide dismutase-linked ALS pathogenesis. Proc Natl Acad Sci USA. (2005) 102(30): 10516-10521.

Tummala H, Jung C, Tiwari A, Higgins C, Trang E, Hayward LJ and Xu Z. Inhibition of chaperone activity is a shared property of several Cu, Zn superoxide dismutase mutants that cause amyotrophic lateral sclerosis. J Biol Chem. (2005) 280(18): 17725-17731.

Chacko B, Qin BY, Tiwari A, Shi G, Lam S, Hayward LJ, deCaestecker M, and Lin K. Structural Basis of Heteromeric Smad Protein Assembly in TGF-b Signaling. Mol Cell. (2004) 15(5): 813-823.

Kumar DP, Tiwari A, and Bhat R. Effect of pH on the stability and structure of yeast hexokinase A: Acidic amino acid residues in the cleft region are critical for the opening and the closing of the structure. J Biol Chem. (2004) 279(31): 32093-32099.

Tiwari A and Hayward LJ. Familial ALS Mutants of Cu/Zn Superoxide Dismutase are Susceptible to Disulfide Reduction. J Biol Chem. (2003) 278(8): 5984-5992.

Rodriguez J, Valentine JS, Eggers DK, Roe JA, Tiwari A, Brown RH Jr, and Hayward LJ. Familial ALS-associated mutations decrease the thermal stability of distinctly metallated species of human copper zinc superoxide dismutase. J Biol Chem. (2002) 277(18): 15932-15937.

Hayward LJ, Rodriguez JA, Kim JW, Tiwari A, Goto JJ, Cabelli DE, Valentine JS, Brown RH Jr. Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial ALS.J Biol Chem. (2002) 277(18): 15923-15931.

Gupta P, Singh S, Tiwari A, Bhat R, and Bhatnagar R. Effect of pH on stability of anthrax lethal factor: correlation between denaturation and activity. Biochem Biophys Res Commun. (2001) 284(3): 568-573.

Tiwari A, Kumar DP, and Bhat R. An efficient and cost-effective procedure for preparing samples for differential scanning calorimetry experiments. Anal Biochem. (2000) 284(2): 406-408.